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(P1 Technologies Inc)

Our data show that KC iron is more closely associated with fibrosis progression than hepatocyte iron, but the relationship between iron deposition in either cell type and fibrosis progression is weak

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It also plays a key role in gut health by supporting the integrity of the intestinal lining and reducing inflammation

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Furthermore, in some tumours, the need for methyl groups for epigenetic regulation prevents activation of the trans-sulphuration pathway for cysteine synthesis, instead prioritising one-carbon metabolism